2020
Lactate promotes cardiomyocyte dedifferentiation through metabolic reprogramming. Jesús Ordoño, Soledad Pérez-Amodio, Kristen Ball, Aitor Aguirre, Elisabeth Engel. bioRxiv 2020.07.21.213736v1; https://doi.org/10.1101/2020.07.21.213736.
Generation of heart organoids modeling early human cardiac development under defined conditions. Yonatan Israeli, Mitchell Gabalski, Kristen Ball, Aaron Wasserman, Jinyun Zou, Guangming Ni, Chao Zhou, Aitor Aguirre. bioRxiv 2020.06.25.171611; doi: https://doi.org/10.1101/2020.06.25.171611.
Bioactive Lipid Signaling in Cardiovascular Disease, Development, and Regeneration. AH Wasserman, M Venkatesan, A Aguirre. Cells 9 (6), 1391.
Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods. K Ball, R Kinne, A Aguirre. Journal of Visualized Experiments, March 2020.
2019
Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. Gaurav Ahuja, Deniz Bartsch, Wenjie Yao, Simon Geissen, Stefan Frank, Aitor Aguirre, Nicole Russ, Jan‐Erik Messling, Joanna Dodzian, Kim A Lagerborg, Natalia Emilse Vargas, Joscha Sergej Muck, Susanne Brodesser, Stephan Baldus, Agapios Sachinidis, Juergen Hescheler, Christoph Dieterich, Aleksandra Trifunovic, Argyris Papantonis, Michael Petrascheck, Anna Klinke, Mohit Jain, Dario Riccardo Valenzano and Leo Kurian. EMBO Reports, March 2019.
2018
New strategies and in vivo monitoring methods for stem cell-based anticancer therapies. P. Wang and A. Aguirre. Stem Cells International, September 2018.
Comparison of Non-Human Primate vs. Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. Xin Zhao, Haodong Chen, Dan Xiao, Ilanit Itzhaki, Huaxiao Yan, Xulei Qin, Tony Chour, Aitor Aguirre, Kim Lehmann, Praveenkumar Shukla, Alexandra Holmstrom, Yan Zhuge, Babacar C. Ndoye, Wolfram-Hubertus Zimmermann, Mohit Jain, Joseph C. Wu. Stem Cell Reports, February 2018.
2017
iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types. Athanasia D. Panopoulos, Matteo D’Antonio, Paola Benaglio, Roy Williams, Sherin I. Hashem, Bernhard M. Schuldt, Christopher DeBoever, Angelo D. Arias, Melvin Garcia, Bradley C. Nelson, Olivier Harismendy, David A. Jakubosky, Margaret K.R. Donovan, William W. Greenwald, Kathy Jean Farnam, Megan Cook, Victor Borja, Carl A. Miller, Jonathan D. Grinstein, Frauke Drees, Jonathan Okubo, Kenneth E. Diffenderfer, Yuriko Hishida, Veronica Modesto, Carl T. Dargitz, Rachel Feiring, Chang Zhao, Aitor Aguirre, Thomas J. McGarry, Hiroko Matsui, He Li, Joaquin Reyna, Fangwen Rao, Daniel T. O’Connor, Gene W. Yeo, Sylvia M. Evans, Neil C. Chi, Kristen Jepsen, Naoki Nariai, Franz-Josef Mu¨ller, Lawrence S.B. Goldstein, Juan Carlos Izpisua Belmonte, Eric Adler, Jeanne F. Loring, W. Travis Berggren, Agnieszka D’Antonio Chronowska, Erin N. Smith and Kelly A. Frazer. Stem Cell Reports, April 2017.
2016
A long noncoding RNA perspective into (re)building the heart. S. Frank*, A. Aguirre*, J. Hescheler and L. Kurian. Frontiers in Cell and Developmental Biology, November 2016 (*contributed equally).
Establishment of tractable human iPSC-based models for the study and targeting of glioma initiation. I. Sancho-Martinez*, E. Nivet*, Y. Xia*, T. Hishida , A. Aguirre , A. Ocampo , L. Ma , R. Morey , M. Krause , A. Zembrzycki , O. Ansorge , E. Vazquez-Ferrer , I. Dubova , P. Reddy , D. Lam , Y. Hishida , M.Z. Wu , C. Rodriguez , D. O'Leary , G. Wahl , I. Verma , L. Laurent and J.C. Izpisua-Belmonte. Nature Communications, February 22, 2015. (*contributed equally).
2015
Identification of novel long non-coding RNAs underlying vertebrate cardiovascular development. L. Kurian*, A. Aguirre*, I. Sancho-Martinez*, C. Benner, T. Hishida, T. B. Nguyen, P. Reddy, D. Nelles, E. Nivet, N. Montserrat, C. Rodriguez-Esteban, G. Yeo, J.C. Izpisua-Belmonte. Circulation, May 2015 (* contributed equally).
2014
In vivo activation of a conserved microRNA program induces mammalian heart regeneration. A. Aguirre*, N. Montserrat*, S. Zachiggna, E. Nivet, T. Hishida, M.N. Krause, L. Kurian, A. Ocampo, E. Vazquez-Ferrer, C. Rodriguez-Esteban, S. Kumar, J.J. Moresco, J.R. Yates 3rd, I. Sancho-Martinez, M. Giacca, J.C. Izpisua-Belmonte. Cell Stem Cell, November 2014. (*contributed equally).
2013
Heart regeneration: a tale of cell reprogramming. Aitor Aguirre, Ignacio Sancho-Martinez, Juan Carlos Izpisua-Belmonte. Circulation research, October 2013.
Reprogramming toward heart regeneration: stem cells and beyond. Aitor Aguirre, Ignacio Sancho-Martinez, Juan Carlos Izpisua-Belmonte. Cell Stem Cell, May 2013.
Conversion of human fibroblasts into angioblast-like progenitor cells. Leo Kurian*, Ignacio Sancho-Martinez*, Emmanuel Nivet*, Aitor Aguirre, Krystal Moon, Caroline Pendaries, Cecile Volle-Challier, Francoise Bono, Jean-Marc Herbert, Julian Pulecio, Yun Xia, Mo Li, Nuria Montserrat, Sergio Ruiz, Ilir Dubova, Concepcion Rodriguez, Ahmet M Denli, Francesca S Boscolo, Rathi D Thiagarajan, Fred H Gage, Jeanne F Loring, Louise C Laurent & Juan Carlos Izpisua-Belmonte. Nature Methods, January 2013 (*contributed equally).
2012
Control of microenvironmental cues with a smart biomaterial composite promotes endothelial progenitor cell angiogenesis. Aguirre A., González A., Navarro M., Castaño O., Planell J.A., Engel E. 2012. European Journal of Cells and Materials. July 24; 24:90-106.
2011
Effect of blasting treatment and Fn coating on MG63 adhesion and differentiation on titanium: a gene expression study using real-time RT-PCR. Pegueroles M, Aguirre A, Engel E, Pavon G, Gil FJ, Planell JA, Migonney V, Aparicio C. Journal of Materials in Science: Materials in Medicine. 2011, March; 22(3):617-27.
2010
Dynamics of endothelial progenitor cell/mesenchymal stem cell interaction in co-culture and its implications in angiogenesis. Aguirre A., Planell J.A., Engel E. Biochemical and Biophysical Research Communications. 2010 September 17;400(2):284-91.
Extracellular calcium modulates in vitro bone marrow-derived Flk-1+ CD34+ progenitor cell chemotaxis and differentiation through a calcium-sensing receptor. Aguirre A., González A., Planell J.A., Engel E. Biochemical and Biophysical Research Communications. 2010 Feb. 26; 393(1):156-61.
Foamed surfactant solution as a template for self-setting injectable hydroxyapatite scaffolds for bone regeneration. Montufar EB, Traykova T., Gil C., Harr I., Aguirre A., Engel E., Planell J.A., Ginebra M.P. Acta Biomaterialia. 2010 Mar; 6(3):876-85.
2008
Towards improved neovascularization – Endothelial progenitor cells and PLA/Bioactive glass composite with angiogenic-inducing properties. Aguirre A, Marquez L, Navarro M, Planell JA, Engel E. Tissue Engineering Part A. 2008, 14 (5), 923-923.
2005
Role of sodium in mitochondrial membrane depolarization induced by P2X7 receptor activation in submandibular glands. Garcia-Marcos M, Fontanils U, Aguirre A, Pochet S, Dehaye JP, Marino A. FEBS Letters. 2005 Oct 10;579(24):5407-13.
Lactate promotes cardiomyocyte dedifferentiation through metabolic reprogramming. Jesús Ordoño, Soledad Pérez-Amodio, Kristen Ball, Aitor Aguirre, Elisabeth Engel. bioRxiv 2020.07.21.213736v1; https://doi.org/10.1101/2020.07.21.213736.
Generation of heart organoids modeling early human cardiac development under defined conditions. Yonatan Israeli, Mitchell Gabalski, Kristen Ball, Aaron Wasserman, Jinyun Zou, Guangming Ni, Chao Zhou, Aitor Aguirre. bioRxiv 2020.06.25.171611; doi: https://doi.org/10.1101/2020.06.25.171611.
Bioactive Lipid Signaling in Cardiovascular Disease, Development, and Regeneration. AH Wasserman, M Venkatesan, A Aguirre. Cells 9 (6), 1391.
Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods. K Ball, R Kinne, A Aguirre. Journal of Visualized Experiments, March 2020.
2019
Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. Gaurav Ahuja, Deniz Bartsch, Wenjie Yao, Simon Geissen, Stefan Frank, Aitor Aguirre, Nicole Russ, Jan‐Erik Messling, Joanna Dodzian, Kim A Lagerborg, Natalia Emilse Vargas, Joscha Sergej Muck, Susanne Brodesser, Stephan Baldus, Agapios Sachinidis, Juergen Hescheler, Christoph Dieterich, Aleksandra Trifunovic, Argyris Papantonis, Michael Petrascheck, Anna Klinke, Mohit Jain, Dario Riccardo Valenzano and Leo Kurian. EMBO Reports, March 2019.
2018
New strategies and in vivo monitoring methods for stem cell-based anticancer therapies. P. Wang and A. Aguirre. Stem Cells International, September 2018.
Comparison of Non-Human Primate vs. Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. Xin Zhao, Haodong Chen, Dan Xiao, Ilanit Itzhaki, Huaxiao Yan, Xulei Qin, Tony Chour, Aitor Aguirre, Kim Lehmann, Praveenkumar Shukla, Alexandra Holmstrom, Yan Zhuge, Babacar C. Ndoye, Wolfram-Hubertus Zimmermann, Mohit Jain, Joseph C. Wu. Stem Cell Reports, February 2018.
2017
iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types. Athanasia D. Panopoulos, Matteo D’Antonio, Paola Benaglio, Roy Williams, Sherin I. Hashem, Bernhard M. Schuldt, Christopher DeBoever, Angelo D. Arias, Melvin Garcia, Bradley C. Nelson, Olivier Harismendy, David A. Jakubosky, Margaret K.R. Donovan, William W. Greenwald, Kathy Jean Farnam, Megan Cook, Victor Borja, Carl A. Miller, Jonathan D. Grinstein, Frauke Drees, Jonathan Okubo, Kenneth E. Diffenderfer, Yuriko Hishida, Veronica Modesto, Carl T. Dargitz, Rachel Feiring, Chang Zhao, Aitor Aguirre, Thomas J. McGarry, Hiroko Matsui, He Li, Joaquin Reyna, Fangwen Rao, Daniel T. O’Connor, Gene W. Yeo, Sylvia M. Evans, Neil C. Chi, Kristen Jepsen, Naoki Nariai, Franz-Josef Mu¨ller, Lawrence S.B. Goldstein, Juan Carlos Izpisua Belmonte, Eric Adler, Jeanne F. Loring, W. Travis Berggren, Agnieszka D’Antonio Chronowska, Erin N. Smith and Kelly A. Frazer. Stem Cell Reports, April 2017.
2016
A long noncoding RNA perspective into (re)building the heart. S. Frank*, A. Aguirre*, J. Hescheler and L. Kurian. Frontiers in Cell and Developmental Biology, November 2016 (*contributed equally).
Establishment of tractable human iPSC-based models for the study and targeting of glioma initiation. I. Sancho-Martinez*, E. Nivet*, Y. Xia*, T. Hishida , A. Aguirre , A. Ocampo , L. Ma , R. Morey , M. Krause , A. Zembrzycki , O. Ansorge , E. Vazquez-Ferrer , I. Dubova , P. Reddy , D. Lam , Y. Hishida , M.Z. Wu , C. Rodriguez , D. O'Leary , G. Wahl , I. Verma , L. Laurent and J.C. Izpisua-Belmonte. Nature Communications, February 22, 2015. (*contributed equally).
2015
Identification of novel long non-coding RNAs underlying vertebrate cardiovascular development. L. Kurian*, A. Aguirre*, I. Sancho-Martinez*, C. Benner, T. Hishida, T. B. Nguyen, P. Reddy, D. Nelles, E. Nivet, N. Montserrat, C. Rodriguez-Esteban, G. Yeo, J.C. Izpisua-Belmonte. Circulation, May 2015 (* contributed equally).
2014
In vivo activation of a conserved microRNA program induces mammalian heart regeneration. A. Aguirre*, N. Montserrat*, S. Zachiggna, E. Nivet, T. Hishida, M.N. Krause, L. Kurian, A. Ocampo, E. Vazquez-Ferrer, C. Rodriguez-Esteban, S. Kumar, J.J. Moresco, J.R. Yates 3rd, I. Sancho-Martinez, M. Giacca, J.C. Izpisua-Belmonte. Cell Stem Cell, November 2014. (*contributed equally).
2013
Heart regeneration: a tale of cell reprogramming. Aitor Aguirre, Ignacio Sancho-Martinez, Juan Carlos Izpisua-Belmonte. Circulation research, October 2013.
Reprogramming toward heart regeneration: stem cells and beyond. Aitor Aguirre, Ignacio Sancho-Martinez, Juan Carlos Izpisua-Belmonte. Cell Stem Cell, May 2013.
Conversion of human fibroblasts into angioblast-like progenitor cells. Leo Kurian*, Ignacio Sancho-Martinez*, Emmanuel Nivet*, Aitor Aguirre, Krystal Moon, Caroline Pendaries, Cecile Volle-Challier, Francoise Bono, Jean-Marc Herbert, Julian Pulecio, Yun Xia, Mo Li, Nuria Montserrat, Sergio Ruiz, Ilir Dubova, Concepcion Rodriguez, Ahmet M Denli, Francesca S Boscolo, Rathi D Thiagarajan, Fred H Gage, Jeanne F Loring, Louise C Laurent & Juan Carlos Izpisua-Belmonte. Nature Methods, January 2013 (*contributed equally).
2012
Control of microenvironmental cues with a smart biomaterial composite promotes endothelial progenitor cell angiogenesis. Aguirre A., González A., Navarro M., Castaño O., Planell J.A., Engel E. 2012. European Journal of Cells and Materials. July 24; 24:90-106.
2011
Effect of blasting treatment and Fn coating on MG63 adhesion and differentiation on titanium: a gene expression study using real-time RT-PCR. Pegueroles M, Aguirre A, Engel E, Pavon G, Gil FJ, Planell JA, Migonney V, Aparicio C. Journal of Materials in Science: Materials in Medicine. 2011, March; 22(3):617-27.
2010
Dynamics of endothelial progenitor cell/mesenchymal stem cell interaction in co-culture and its implications in angiogenesis. Aguirre A., Planell J.A., Engel E. Biochemical and Biophysical Research Communications. 2010 September 17;400(2):284-91.
Extracellular calcium modulates in vitro bone marrow-derived Flk-1+ CD34+ progenitor cell chemotaxis and differentiation through a calcium-sensing receptor. Aguirre A., González A., Planell J.A., Engel E. Biochemical and Biophysical Research Communications. 2010 Feb. 26; 393(1):156-61.
Foamed surfactant solution as a template for self-setting injectable hydroxyapatite scaffolds for bone regeneration. Montufar EB, Traykova T., Gil C., Harr I., Aguirre A., Engel E., Planell J.A., Ginebra M.P. Acta Biomaterialia. 2010 Mar; 6(3):876-85.
2008
Towards improved neovascularization – Endothelial progenitor cells and PLA/Bioactive glass composite with angiogenic-inducing properties. Aguirre A, Marquez L, Navarro M, Planell JA, Engel E. Tissue Engineering Part A. 2008, 14 (5), 923-923.
2005
Role of sodium in mitochondrial membrane depolarization induced by P2X7 receptor activation in submandibular glands. Garcia-Marcos M, Fontanils U, Aguirre A, Pochet S, Dehaye JP, Marino A. FEBS Letters. 2005 Oct 10;579(24):5407-13.
